	US 11,705,020 B2
	Method of manufacturing a bio-model comprising a synthetic skin layer and bio-model comprising a synthetic skin layer
Vickneswaran A/L Mathaneswaran, Kuala Lumpur (MY); Zainal Ariff Bin Abdul Rahman, Kuala Lumpur (MY); Yuwaraj Kumar A/L Balakrishnan, Kuala Lumpur (MY); and Su Tung Tan, Kuala Lumpur (MY)
Assigned to UNIVERSITI MALAYA, Kuala Lumpur (MY)
Appl. No. 16/317,540
Filed by UNIVERSITI MALAYA, Kuala Lumpur (MY)
PCT Filed Jul. 12, 2017, PCT No. PCT/MY2017/050037 § 371(c)(1), (2) Date Jan. 12, 2019, PCT Pub. No. WO2018/012960, PCT Pub. Date Jan. 18, 2018.
Claims priority of application No. 2016001297 (MY), filed on Jul. 12, 2016.
Prior Publication US 2019/0220974 A1, Jul. 18, 2019
Int. Cl. G09B 23/30 (2006.01); B33Y 80/00 (2015.01); A61B 34/10 (2016.01); B33Y 50/00 (2015.01); G16H 50/50 (2018.01); G06T 7/00 (2017.01)

CPC G09B 23/30 (2013.01) [A61B 34/10 (2016.02); B33Y 50/00 (2014.12); B33Y 80/00 (2014.12); G06T 7/0012 (2013.01); G16H 50/50 (2018.01); A61B 2034/101 (2016.02)]

8 Claims

1. A method of manufacturing a three dimensional bio-model from medical image data, comprising:

identifying a skin layer in the medical image data;

determining a thickness of the skin layer;

generating three dimensional model data from the medical image data, the three dimensional model data comprising an indication of a synthetic skin layer, the synthetic skin layer comprising a surface layer and a backing layer;

three dimensional printing layers of the synthetic skin layer at once based on the three dimensional model data;

fabricating a synthetic bone layer and synthetic dura layer in which the synthetic bone layer is disposed in-between the synthetic skin layer and the synthetic dura layer for forming an insert; and

fabricating a base piece based on the medical image data;

wherein the insert and the base piece define the three dimensional bio-model in which the insert has sides formed with walls for it to be detachably fitted into a slot defined on the base piece.