	US 11,702,463 B2
	Canine antibody libraries
Thomas Tiller, Munich (DE); Markus Waldhuber, Munich (DE); Ralf Strohner, Eichenau (DE); Kathrin Ladetzki-Baehs, Planegg (DE); and Josef Prassler, Germering (DE)
Assigned to MORPHOSYS AG, Planegg (DE)
Filed by MORPHOSYS AG, Planegg (DE)
Filed on Apr. 22, 2021, as Appl. No. 17/237,527.
Application 17/237,527 is a continuation of application No. 16/624,514, granted, now 11,014,978, previously published as PCT/EP2018/066563, filed on Jun. 21, 2018.
Claims priority of application No. 17177322 (EP), filed on Jun. 22, 2017.
Prior Publication US 2021/0317190 A1, Oct. 14, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 16/00 (2006.01); C07K 16/18 (2006.01)

CPC C07K 16/005 (2013.01) [C07K 16/18 (2013.01); C07K 2317/20 (2013.01); C07K 2317/40 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01)]

20 Claims

1. A synthetic canine antibody library, wherein said library comprises members of at least two of the following VH1 regions with an identity of at least 90% to a germline VH1 region selected from Vs618 (SEQ ID NO:4), Vs624 (SEQ ID NO:1), Vs628 (SEQ ID NO:5) and Vs635 (SEQ ID NO:2).