US 11,701,454 B2
Drug-coated medical devices
Shashank Raina, San Rafael, CA (US); John Kantor, Healdsburg, CA (US); and Susan Peterson, Santa Rosa, CA (US)
Assigned to Medtronic Vascular, Inc., Santa Rosa, CA (US)
Filed by Medtronic Vascular Inc., Santa Rosa, CA (US)
Filed on Aug. 14, 2020, as Appl. No. 16/993,870.
Application 16/993,870 is a continuation of application No. 15/901,711, filed on Feb. 21, 2018, granted, now 10,772,993.
Claims priority of provisional application 62/462,399, filed on Feb. 23, 2017.
Prior Publication US 2020/0368400 A1, Nov. 26, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 29/08 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01); A61L 29/16 (2006.01); A61K 31/337 (2006.01); A61M 25/10 (2013.01); A61L 29/06 (2006.01); A61L 31/06 (2006.01); A61K 47/69 (2017.01); A61P 9/10 (2006.01); A61F 2/82 (2013.01)
CPC A61L 29/085 (2013.01) [A61K 31/337 (2013.01); A61K 47/6931 (2017.08); A61L 29/06 (2013.01); A61L 29/16 (2013.01); A61L 31/06 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61M 25/104 (2013.01); A61P 9/10 (2018.01); A61F 2/82 (2013.01); A61F 2250/0067 (2013.01); A61L 2300/416 (2013.01); A61L 2300/602 (2013.01); A61L 2300/606 (2013.01); A61L 2300/80 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01); A61M 2025/105 (2013.01)] 17 Claims
 
1. A medical device comprising:
a body having an exterior surface; and
a coating disposed on the exterior surface of the body, the coating comprising a first therapeutic agent-containing nanoparticle, wherein the nanoparticle comprises a brush-arm star polymer, wherein the therapeutic agent of the therapeutic agent-nanoparticle comprises an antiproliferative agent, and wherein the coating further comprises a second therapeutic agent that is not associated with the nanoparticle, wherein the coating further comprises a second therapeutic agent-containing nanoparticle comprising an anti-inflammatory steroid and a brush-arm star polymer.