CPC A61L 29/085 (2013.01) [A61K 31/337 (2013.01); A61K 47/6931 (2017.08); A61L 29/06 (2013.01); A61L 29/16 (2013.01); A61L 31/06 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61M 25/104 (2013.01); A61P 9/10 (2018.01); A61F 2/82 (2013.01); A61F 2250/0067 (2013.01); A61L 2300/416 (2013.01); A61L 2300/602 (2013.01); A61L 2300/606 (2013.01); A61L 2300/80 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01); A61M 2025/105 (2013.01)] | 17 Claims |
1. A medical device comprising:
a body having an exterior surface; and
a coating disposed on the exterior surface of the body, the coating comprising a first therapeutic agent-containing nanoparticle, wherein the nanoparticle comprises a brush-arm star polymer, wherein the therapeutic agent of the therapeutic agent-nanoparticle comprises an antiproliferative agent, and wherein the coating further comprises a second therapeutic agent that is not associated with the nanoparticle, wherein the coating further comprises a second therapeutic agent-containing nanoparticle comprising an anti-inflammatory steroid and a brush-arm star polymer.
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