	US 11,701,453 B2
	Dental pulp construct
Luiz Bertassoni, Portland, OR (US); Anthony Tahayeri, Sherwood, OR (US); Avathamsa Athirasala, Hillsboro, OR (US); and Jack L. Ferracane, Portland, OR (US)
Assigned to Oregon Health & Science University, Portland, OR (US)
Appl. No. 16/618,329
Filed by OREGON HEALTH & SCIENCE UNIVERSITY, Portland, OR (US)
PCT Filed May 30, 2018, PCT No. PCT/US2018/035200 § 371(c)(1), (2) Date Nov. 29, 2019, PCT Pub. No. WO2018/222761, PCT Pub. Date Dec. 6, 2018.
Claims priority of provisional application 62/512,675, filed on May 30, 2017.
Prior Publication US 2021/0283311 A1, Sep. 16, 2021
Int. Cl. A61L 27/52 (2006.01); A61L 27/12 (2006.01); A61L 27/22 (2006.01); C08L 89/06 (2006.01); A61L 27/54 (2006.01); C08L 93/00 (2006.01)

CPC A61L 27/52 (2013.01) [A61L 27/12 (2013.01); A61L 27/222 (2013.01); A61L 27/54 (2013.01); C08L 89/06 (2013.01); A61L 2400/06 (2013.01); A61L 2430/12 (2013.01); C08L 93/00 (2013.01)]

19 Claims

1. A method for treating decay of a tooth by promoting regeneration of vascularized dental pulp in a root canal in the tooth, the method comprising:

positioning a fiber in the root canal of the tooth;

filling at least a portion of the root canal with an unset hydrogel composition, such that the unset hydrogel composition contacts at least a portion of the fiber;

setting the hydrogel composition, thereby forming a set hydrogel; and

removing the fiber from the set hydrogel, thereby leaving a channel in the set hydrogel, the channel being sized to form a vascular-like conduit.