	US 11,701,448 B2
	Powder for achieving hemostasis
Gerald Fredrickson, Westford, MA (US); Amanda L. Smith, Boston, MA (US); Andrew Pic, Northborough, MA (US); Sophia Gervasio, Coventry, RI (US); and Lauren Lydecker, Millbury, MA (US)
Assigned to Boston Scientific Scimed, Inc., Maple Grove, MN (US)
Filed by Boston Scientific Scimed, Inc., Maple Grove, MN (US)
Filed on Aug. 25, 2020, as Appl. No. 17/2,399.
Application 17/002,399 is a continuation of application No. 16/245,780, filed on Jan. 11, 2019, granted, now 10,786,596.
Claims priority of provisional application 62/616,751, filed on Jan. 12, 2018.
Prior Publication US 2020/0384148 A1, Dec. 10, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 31/16 (2006.01); A61L 26/00 (2006.01); A61K 31/722 (2006.01); A61L 31/04 (2006.01); A61M 25/09 (2006.01)

CPC A61L 26/0023 (2013.01) [A61K 31/722 (2013.01); A61L 26/008 (2013.01); A61L 26/0066 (2013.01); A61L 31/042 (2013.01); A61L 31/16 (2013.01); A61L 2300/232 (2013.01); A61L 2300/418 (2013.01); A61L 2300/60 (2013.01); A61L 2400/04 (2013.01); A61M 25/09 (2013.01); A61M 2025/091 (2013.01); A61M 2202/064 (2013.01); A61M 2210/1042 (2013.01)]

20 Claims

1. A method of treating a tissue site comprising:

administering a composition to the tissue site;

wherein the composition includes a powder that comprises first particles comprising chitosan or a chitosan salt and second particles that comprise a crosslinking agent, wherein the crosslinking agent is a derivatized polymer selected from an epoxy derivatized polymer, an acrylate derivatized polymer, or a genipin derivatized polymer.