CPC A61K 48/0041 (2013.01) [A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 31/7105 (2013.01); A61K 47/10 (2013.01); A61K 47/543 (2017.08); C07K 2/00 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01)] | 28 Claims |
1. A tertiary amino lipidated and/or PEGylated cationic peptide compound of formula (I) or a salt thereof:
wherein:
s is an integer from 1 to 5;
R1 is —H
each R3 is independently selected from C8-C24alkyl;
R5 is selected from hydroxyalkyl, hydroxyether, and hydroxylheteroalkyl;
R7 is —H, alkyl, acyl, —OH, —OR7a, —NH2, -NHR7a, or a lipid moiety, wherein
R7a is alkyl, acyl, or a lipid moiety; and
each Ra and Rb are independently —H, C1-C4-alkyl, or a side chain moiety found on a naturally- or non-naturally-occurring amino acid.
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