CPC A61K 39/0008 (2013.01) [A61P 37/06 (2018.01); C12N 15/11 (2013.01); C12N 15/117 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55555 (2013.01); C12N 2310/335 (2013.01)] | 8 Claims |
1. A method of treating an autoimmune disease in a subject,
comprising administering to the subject a composition comprising a non-immunogenic RNA encoding a peptide or polypeptide comprising an autoantigen or a fragment thereof, or a variant of the autoantigen or fragment, wherein the non-immunogenic RNA comprises 1-methyl-pseudouridine, wherein the non-immunogenic RNA is formulated in a F12 liposome, and wherein the composition does not comprise dsRNA.
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