CPC A61K 9/127 (2013.01) [A61K 31/203 (2013.01); A61K 31/436 (2013.01); A61K 38/168 (2013.01); A61K 38/1709 (2013.01); A61K 38/38 (2013.01); A61K 38/39 (2013.01); A61K 38/47 (2013.01); C12Y 302/0102 (2013.01)] | 7 Claims |
1. A method for inducing immune tolerance to a target antigen in an individual comprising:
a) providing to the individual a first regimen of multiple administrations of a first composition comprising liposomes, wherein the liposomes comprise phosphatidylcholine (PC) and lyso-phosphatidylserine (lyso-PS), wherein the ratio of PC to lyso-PS is from 90:10 to 60:40, and wherein the liposomes are complexed to a target antigen; and
b) while continuing the first regimen, providing to the individual a second regimen of one or more administrations of a second composition comprising the antigen free of liposomes.
|