| CPC A01N 59/00 (2013.01) [A01N 25/12 (2013.01); A01N 25/22 (2013.01)] | 5 Claims |
|
1. A method for synthesizing an antimicrobial base, the method comprising:
treating a silver salt in a reaction mixture, wherein the silver salt is a 35% to 60% w/w solution, and wherein the reaction mixture is aqueous in nature;
adding one or more reactants to the reaction mixture, wherein the one or more reactants is at least one of a monosaccharide, a polysaccharide, a derivative of polysaccharide, a modified polysaccharide, and a biopolymer, and wherein the one or more reactants form a reactive agent, and wherein a volume of the one or more reactants is 3 to 8 times in equivalent to the volume of the silver salt, and wherein the one or more reactants is added to the reaction mixture as a 25% to 50% w/w solution;
heating the reaction mixture at a first temperature between 45° C. to 90° C. for a first period of 5 to 8 hours, wherein a plurality of silver ions (Ag+) from the silver salt is converted to a plurality of colloidal silver particles (Ag0), and wherein the pH of the reaction mixture is maintained between 8.0 to 10.5 using a neutralizer and an alkali, and wherein the neutralizer is a buffering solution, and wherein the alkali is an ionic metallic salt;
stabilizing the conversion by adding a ligand and a stabilizing agent, wherein the ligand is a glycolic derivative, and wherein the stabilizing agent is a cellulose derivative, and the stabilizing agent is added as a 0.5% to 2% w/w aqueous solution to the reaction mixture;
digesting the reaction mixture at a second temperature between 45° C. to 65° C. for a second period of 2 to 4 hours to form an end product; and
filtering the reaction mixture to separate the end product into a sub-micron particle and a micron particle, wherein the sub-micron particle contains the colloidal silver particles (Ag0), thereby forming the antimicrobial base;
wherein at least one of the colloidal silver particles has a triclinic shape.
|