US 11,692,037 B2
Anti-IL-6 receptor antibody-containing medicinal composition for preventing post-surgical adhesion
Jiro Fujimoto, Hyogo (JP); Tomohiro Yoshimoto, Hyogo (JP); and Naoki Uyama, Hyogo (JP)
Assigned to Hyogo College of Medicine, Hyogo (JP); and Chugai Seiyaku Kabushiki Kaisha, Tokyo (JP)
Appl. No. 16/756,404
Filed by Hyogo College of Medicine, Hyogo (JP); and Chugai Seiyaku Kabushiki Kaisha, Tokyo (JP)
PCT Filed Oct. 19, 2018, PCT No. PCT/JP2018/038955
§ 371(c)(1), (2) Date Apr. 15, 2020,
PCT Pub. No. WO2019/078344, PCT Pub. Date Apr. 25, 2019.
Claims priority of application No. JP2017-203271 (JP), filed on Oct. 20, 2017.
Prior Publication US 2020/0299391 A1, Sep. 24, 2020
Int. Cl. C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 1/00 (2006.01)
CPC C07K 16/2866 (2013.01) [A61P 1/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01)] 11 Claims
 
1. A method for suppressing postoperative adhesion, which comprises administering an effective amount of an anti-IL-6 receptor antibody to a subject, wherein the adhesion is gastrointestinal adhesion or liver adhesion.