	US 11,692,013 B2
	Broad spectrum insecticidal polypeptide against lepidopteran pests and methods of use thereof
Andre Roger Abad, Leander, TX (US); Andrew Carl Crow, Grimes, IA (US); Brad Poland, Monroe, IA (US); and Jimei Wang, Johnston, IA (US)
Assigned to PIONEER HI-BRED INTERNATIONAL, INC.
Filed by PIONEER HI-BRED INTERNATIONAL, INC., Johnston, IA (US)
Filed on Apr. 15, 2021, as Appl. No. 17/231,651.
Application 17/231,651 is a continuation of application No. 16/342,343, granted, now 11,008,371, previously published as PCT/US2017/053178, filed on Sep. 25, 2017.
Claims priority of provisional application 62/410,045, filed on Oct. 19, 2016.
Prior Publication US 2021/0277070 A1, Sep. 9, 2021
Int. Cl. C07K 14/325 (2006.01); A01N 37/46 (2006.01); C12N 15/82 (2006.01)

CPC C07K 14/325 (2013.01) [A01N 37/46 (2013.01); C12N 15/8286 (2013.01); Y02A 40/146 (2018.01)]

26 Claims

1. A chimeric Cry1E polypeptide comprising: a) a Domain I of a first Cry1E protein; and b) a Domain II and a Domain III of a second Cry1E protein of SEQ ID NO: 2 or a fragment or variant of SEQ ID NO: 2, wherein the chimeric Cry1E polypeptide has at least 95% sequence identity to SEQ ID NO: 4.