CPC C07D 471/04 (2013.01) [A61P 35/00 (2018.01); C07D 401/14 (2013.01)] | 10 Claims |
1. A compound of Formula:
or a pharmaceutically acceptable salt thereof;
wherein:
Q1 is independently at each occurrence selected from the group consisting of NH, N(alkyl), N(haloalkyl), CH2, O, and S;
X3 is N, CH, or CR3;
X10 is C(R7)2, C(O), or O;
X11 is heterocycle optionally substituted with 1, 2, or 3 groups independently selected from R3;
X16 is selected from the group consisting of N, CH, and CR4;
R3 is independently at each occurrence selected from the group consisting of hydrogen, hydroxyl, alkoxy, C1-C4alkyl, C1-C4haloalkyl, cycloalkyl, fluorine, chlorine, bromine, and iodine;
each R4 is independently selected from the group consisting of hydrogen, aryl, heteroaryl, C1-C4alkoxy, C1-C4haloalkyl, C1-C4haloalkoxy, C1-C4alkyl, fluorine, chlorine, bromine, and iodine;
each R7 is independently hydrogen, methyl, or ethyl; and
R8 is hydrogen, C1-C4alkyl, alkenyl, alkynyl, haloalkyl, or cycloalkyl.
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