US 11,690,869 B2
Methods of inhibiting enveloped viruses using low molecular weight hydrophobically modified polymers
Elizabeth Bruning, Skillman, NJ (US); Kimberly Capone, Skilllman, NJ (US); Lisa Renee Gandolfi, Skillman, NJ (US); Anthony Robert Geonnotti, III, Skillman, NJ (US); Euen Thomas Ekman-Gunn, Skillman, NJ (US); Diana Roshek Johnson, Skillman, NJ (US); Frank J. Kirchner, Skillman, NJ (US); Selina Moses, Skillman, NJ (US); Delores Santora, Skillman, NJ (US); Russel Walters, Skillman, NJ (US); and Frank C. Sun, Skillman, NJ (US)
Assigned to Johnson & Johnson Consumer Inc., Skillman, NJ (US)
Filed by Johnson & Johnson Consumer Inc., Skillman, NJ (US)
Filed on Apr. 23, 2020, as Appl. No. 16/856,766.
Prior Publication US 2021/0330699 A1, Oct. 28, 2021
Int. Cl. A61K 31/78 (2006.01)
CPC A61K 31/78 (2013.01) 14 Claims
OG exemplary drawing
 
1. A method of inhibiting entry of enveloped viruses into cells of a subject comprising-applying an anti-viral composition to infectable surfaces of said subject, wherein said infectable surfaces comprise mucosal tissue of said subject, wherein said mucosal tissue comprises tissue selected from the group consisting of oral tissue, ocular tissue, nasal tissue, vaginal tissue, or rectal tissue and a combination thereof, wherein said anti-viral composition comprises at least one low molecular weight hydrophobically modified polymer in an amount effective to inhibit entry of viruses into cells, wherein said enveloped viruses is a Retrovirus,
wherein said low molecular weight hydrophobically modified polymer is potassium acrylates copolymer,
wherein said composition comprises from about 0.375% to about 9% by weight of surfactant having an HLB greater than 12,
wherein said composition comprises a dosage form selected from the group consisting of: a liquid, a lotion, a cream, a gel, a stick, a spray, an ointment, a paste, a powder, a mousse, a wipe, a patch, a hydrogel and a film.