	US 11,690,858 B1
	Neuroprotective mixture for mitigating the harmful effects of ischemic stroke
Joseph L. Clark, Cincinnati, OH (US); Todd J. Crocco, Morgantown, WV (US); Charles L. Rosen, Morgantown, WV (US); and Steven Cutright, Morgantown, WV (US)
Assigned to TRICERAPRO HOLDING, LLC, Morgantown, WV (US)
Filed by Tricerapro Holding, LLC, Morgantown, WV (US)
Filed on Nov. 16, 2020, as Appl. No. 17/99,293.
Application 17/099,293 is a continuation in part of application No. 16/354,994, filed on Mar. 15, 2019, granted, now 10,864,221.
Claims priority of provisional application 62/694,983, filed on Jul. 7, 2018.
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/664 (2006.01); A61P 25/00 (2006.01); A61K 31/191 (2006.01); A61K 33/06 (2006.01)

CPC A61K 31/664 (2013.01) [A61K 31/191 (2013.01); A61K 33/06 (2013.01); A61P 25/00 (2018.01)]

14 Claims

1. A composition for prophylactically mitigating the harmful effects of stroke, the composition comprising a mixture of creatine, magnesium salt, and one or more ketone bodies selected from the groups consisting of (1) creatine monohydrate, creatine ethyl ester, creatine ethyl ester malate, creatine gluconate, creatine hydrochlorate, tri creatine malate, tri creatine orotate, and phosphocreatine, (2) magnesium gluconate, magnesium chloride, magnesium sulfate, and magnesium citrate, and (3) β-Hydroxybutyrate (BHB) and acetoacetate; and further wherein the creatine, magnesium salt, and one or more ketone bodies are present in a 2:1:2 ratio.