	US 11,690,797 B2
	Cosmetic composition comprising rose stem cell-derived exosome as effective ingredient
Yong Weon Yi, Seoul (KR); and Byong Seung Cho, Gunpo-si (KR)
Assigned to ExoCoBio Inc., Seoul (KR)
Filed by ExoCoBio Inc., Seoul (KR)
Filed on Jan. 5, 2021, as Appl. No. 17/141,693.
Application 17/141,693 is a continuation of application No. PCT/KR2019/009053, filed on Jul. 23, 2019.
Claims priority of application No. 10-2018-0087232 (KR), filed on Jul. 26, 2018; and application No. 10-2019-0011567 (KR), filed on Jan. 30, 2019.
Prior Publication US 2021/0121393 A1, Apr. 29, 2021
Int. Cl. A61K 8/9789 (2017.01); A61K 8/02 (2006.01); A61K 8/04 (2006.01); A61K 8/06 (2006.01); A61Q 19/08 (2006.01)

CPC A61K 8/9789 (2017.08) [A61K 8/0208 (2013.01); A61K 8/0212 (2013.01); A61K 8/0241 (2013.01); A61K 8/042 (2013.01); A61K 8/044 (2013.01); A61K 8/046 (2013.01); A61K 8/06 (2013.01); A61Q 19/08 (2013.01)]

16 Claims

1. A method for skin regeneration, skin elasticity improvement or skin wrinkle reduction in a subject in need thereof, the method comprising

treating a skin of the subject with a composition comprising isolated exosomes derived from rose stem cells as an active ingredient, wherein the exosomes are isolated from a conditioned medium of the rose stem cells,

wherein the treating the skin with the composition promotes collagen production but reducing cytotoxicity in the skin.