US 11,684,871 B2
Torus reactor for a combined cell isolator and bioreactor
John Daly, Tipperary (IE); Kieran Curran, Limerick (IE); Macdara Glynn, Galway (IE); Mark McCabe, Dublin (IE); David Merrigan, Clare (IE); Jason Ryan, Tipperary (IE); John P. Griffin, Clare (IE); Caitriona Ryan, Clare (IE); and Martin Reddin, Laois (IE)
Assigned to AnuCell Biosystems Limited, Limerick (IE)
Filed by AnuCell Biosystems Limited, Limerick (IE)
Filed on Apr. 6, 2021, as Appl. No. 17/223,744.
Application 17/223,744 is a continuation of application No. 16/706,558, filed on Dec. 6, 2019, granted, now 11,000,780.
Prior Publication US 2021/0228999 A1, Jul. 29, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. B01D 15/18 (2006.01); B01D 21/26 (2006.01); B03C 1/01 (2006.01); B03C 1/30 (2006.01); C12N 15/85 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01)
CPC B01D 15/1892 (2013.01) [B03C 1/01 (2013.01); B03C 1/30 (2013.01); C12M 33/14 (2013.01); C12M 41/00 (2013.01); C12N 15/85 (2013.01); B03C 2201/18 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A system for isolation of one or more target materials from one or more non-target materials disposed within a fluid, the system comprising:
an isolation chamber configured to receive the fluid via one or more fluidic connections, the isolation chamber comprising a semi-toroidal ring shape including a central hole defining a longitudinal axis, the isolation chamber further comprising an isolation material disposed therein, the one or more target materials and the one or more non-target materials each having a respective concentration within the fluid;
a platform configured to fit at least a portion of and releasably couple the isolation chamber; and
a motor coupled to the platform operable to move the isolation chamber upon activation;
wherein, when the motor is activated, the platform is configured to rotate the isolation chamber at an adjustable angle and an adjustable speed such that the fluid contained within the isolation chamber travels around the semi-toroidal ring shape to change the concentration of the one or more target materials relative to the concentration of the one or more non-target materials in the fluid.