CPC A61L 27/52 (2013.01) [A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/24 (2013.01); A61L 27/3633 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61L 27/48 (2013.01); A61L 2400/06 (2013.01); A61L 2430/06 (2013.01); A61L 2430/34 (2013.01)] | 25 Claims |
1. A scaffold complex comprising:
a polymeric fiber comprising collagen;
a hydrogel material comprising hyaluronic acid;
a crosslinking moiety present in an amount effective to introduce interfacial bonding between the polymeric fiber and the hydrogel material; and
a plurality of pores present on a surface of the scaffold complex, wherein the pores are present at a concentration of at least about 50 pores per cm2 of the surface, and wherein at least 80% of the pores have an average pore diameter on the surface that is at least about 5 microns,
wherein the scaffold complex is suitable for incorporation into the tissue of a human subject by injection of the scaffold complex into the tissue.
|