CPC A61K 51/0491 (2013.01) [A61K 51/08 (2013.01)] | 12 Claims |
1. A method of detecting eosinophil degranulation in a respiratory tract passage of a subject, the method comprising:
administering radiolabeled heparin to the respiratory tract passage of the subject, wherein the radiolabeled heparin binds to one or more eosinophil granule proteins in the mucosal tissue of the respiratory tract passage; and
detecting the radiolabeled heparin in the mucosal tissue of the respiratory tract passage by one of single-photon emission computed tomography (SPECT), positron emission tomography (PET), conventional or computed tomography (CT), magnetic resonance imaging (MRI), or combinations thereof, hereby wherein detecting the radiolabeled heparin in the mucosal tissue is indicative of eosinophil degranulation in the respiratory tract passage of the subject.
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