US 11,684,555 B2
Compositions and methods for treating canker sores
Marvin Cohen, Saint Louis, MO (US); Susanne Cohen, Saint Louis, MO (US); and Robert Flynn, Dupo, IL (US)
Assigned to The Research Foundation For The State University Of New York, Albany, NY (US)
Filed by The Research Foundation for the State University of New York, Albany, NY (US)
Filed on May 27, 2020, as Appl. No. 16/884,851.
Application 16/884,851 is a continuation of application No. 16/123,142, filed on Sep. 6, 2018, granted, now 10,702,463.
Application 16/123,142 is a continuation of application No. 15/227,080, filed on Aug. 3, 2016, granted, now 10,071,031, issued on Sep. 11, 2018.
Application 15/227,080 is a continuation of application No. 14/859,691, filed on Sep. 21, 2015, granted, now 9,480,635, issued on Nov. 1, 2016.
Application 14/859,691 is a continuation of application No. 13/814,070, granted, now 9,138,428, issued on Sep. 22, 2015, previously published as PCT/US2011/046831, filed on Aug. 5, 2011.
Claims priority of provisional application 61/371,695, filed on Aug. 7, 2010.
Claims priority of provisional application 61/371,696, filed on Aug. 7, 2010.
Prior Publication US 2020/0405599 A1, Dec. 31, 2020
Int. Cl. A61K 8/27 (2006.01); A61K 8/20 (2006.01); A61K 8/92 (2006.01); A61Q 11/00 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 33/20 (2006.01); A61K 33/30 (2006.01); A61K 8/19 (2006.01); A61K 8/34 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 8/22 (2006.01); A61K 8/368 (2006.01); A61K 9/08 (2006.01); A61K 31/4425 (2006.01); A61K 33/40 (2006.01); A61K 8/49 (2006.01); A61K 31/435 (2006.01); A61K 8/36 (2006.01)
CPC A61K 8/27 (2013.01) [A61K 8/19 (2013.01); A61K 8/20 (2013.01); A61K 8/22 (2013.01); A61K 8/345 (2013.01); A61K 8/36 (2013.01); A61K 8/368 (2013.01); A61K 8/4926 (2013.01); A61K 8/922 (2013.01); A61K 9/0063 (2013.01); A61K 9/08 (2013.01); A61K 31/435 (2013.01); A61K 31/4425 (2013.01); A61K 33/20 (2013.01); A61K 33/30 (2013.01); A61K 33/40 (2013.01); A61K 45/06 (2013.01); A61Q 11/00 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 2800/882 (2013.01); A61K 2800/92 (2013.01)] 14 Claims
 
1. A method for treating or reducing the occurrence of canker sores in a subject in need thereof, the method comprising delivering a composition to the oral cavity of the subject, wherein the composition comprises:
a first component comprising at least one Eh-raising compound, wherein the at least one Eh-raising compound is sodium chlorite, and a pharmaceutically acceptable carrier;
a second component comprising at least one zinc compound, wherein the at least one zinc compound is zinc chloride or zinc acetate, and a pharmaceutically acceptable carrier;
and wherein the composition further comprises an essential oil.