US 11,684,259 B2
Pupillometer for lesion location determination
Bin Chen, Munster, IN (US)
Assigned to Purdue Research Foundation, West Lafayette, IN (US)
Filed by Purdue Research Foundation, West Lafayette, IN (US)
Filed on Nov. 7, 2019, as Appl. No. 16/676,859.
Claims priority of provisional application 62/787,416, filed on Jan. 2, 2019.
Prior Publication US 2020/0205660 A1, Jul. 2, 2020
Int. Cl. A61B 3/18 (2006.01); A61B 3/15 (2006.01); A61B 3/14 (2006.01); A61B 5/00 (2006.01); A61B 3/00 (2006.01); A61B 3/11 (2006.01)
CPC A61B 3/18 (2013.01) [A61B 3/0008 (2013.01); A61B 3/112 (2013.01); A61B 3/145 (2013.01); A61B 3/156 (2013.01); A61B 5/4064 (2013.01); A61B 2576/026 (2013.01)] 4 Claims
OG exemplary drawing
 
1. An electronic flashlight-like pupillometer for measurement of direct and consensual pupillary light responses of the eyes of a patient, which pupillometer comprises:
a housing;
an imaging device in the housing;
a set of infrared light sources in the housing for image and/or video acquisition;
an infrared light filter in front of the imaging device in the housing that allows the passage of infrared light and substantially blocks all visible lights;
a first visible light source in the housing that can provide a visible light to the first eye of the patient;
a second visible light source that is outside of the housing, extendable from the housing, and can provide a visible light to the second eye of the patient when the imaging device is simultaneously taking image and/or video of the first eye;
an image and/or video acquisition component consisting of a light subsystem and an image/video acquisition subsystem configured to manipulate the visible light source, the infrared light source, and the imaging device for acquiring image/video from both eyes, and recording direct and consensual pupillary reflex response:
and
a data processing component configured to determine pupil size and shape using a convolution neural network and to quantify pupillary response for disease diagnosis and determination of lesion locations;
wherein the infrared light source in the housing can continuously illuminate the first and/or second eye of the patient with infrared light from the infrared light source during a test to provide the necessary illumination for the image/video acquisition.