US 11,680,925 B2
Systems and methods for electrochemical hematocrit determination by alternate current impedance phase angle determinations
Gary L. Hughes, Anderson, IN (US); and Ryan D. Jesswein, Indianapolis, IN (US)
Assigned to Polymer Technology Systems, Inc., Whitestown, IN (US)
Filed by Polymer Technology Systems, Inc., Indianapolis, IN (US)
Filed on Nov. 25, 2015, as Appl. No. 14/952,360.
Claims priority of provisional application 62/084,362, filed on Nov. 25, 2014.
Prior Publication US 2016/0146750 A1, May 26, 2016
Int. Cl. G01N 27/327 (2006.01); G01N 33/49 (2006.01); G01N 15/05 (2006.01)
CPC G01N 27/3274 (2013.01) [G01N 27/3271 (2013.01); G01N 27/3273 (2013.01); G01N 27/3275 (2013.01); G01N 27/3277 (2013.01); G01N 33/49 (2013.01); G01N 2015/055 (2013.01); G01N 2333/904 (2013.01); G01N 2496/80 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A system for determining a level of hematocrit, comprising:
a test strip configured to receive a sample;
a meter configured to receive the test strip; and
further including circuitry and a microprocessor, the circuitry and the microprocessor configured to apply electrical energy to the test strip, the test strip having a working electrode and a counter electrode, and the sample and determine an impedance phase angle of the test strip and the sample and the circuitry and the microprocessor are further configured to determine an impedance magnitude of the test strip and, the circuitry and the microprocessor applying a direct current, to the working electrode and the counter electrode, through a switch matrix, to determine the impendence magnitude and an alternating current, to the working electrode and the counter electrode, through the switch matrix, to determine the impedance phase angle, based on the impedance phase angle and the impedance magnitude, calculate the level of hematocrit, the microprocessor determining the level of hematocrit based on an amount of glucose in the sample that affects the impedance magnitude and the impedance phase angle at a different rate than the level of hematocrit, a level of glucose and the level of hematocrit.