	US 11,679,135 B2
	Composition for use in the treatment and/or improvement of sleep and mood disorders
Marco Pane, Novara (IT); Angela Amoruso, Novara (IT); Mirta Fiorio, Novara (IT); Angela Marotta, Novara (IT); Giovanna Felis, Novara (IT); and Antonio Del Casale, Novara (IT)
Assigned to PROBIOTICAL S.P.A., Novara No (IT)
Appl. No. 16/770,007
Filed by PROBIOTICAL S.P.A., Novara (IT)
PCT Filed Dec. 19, 2018, PCT No. PCT/IB2018/060363 § 371(c)(1), (2) Date Jun. 4, 2020, PCT Pub. No. WO2019/123329, PCT Pub. Date Jun. 27, 2019.
Claims priority of application No. 102017000146806 (IT), filed on Dec. 19, 2017.
Prior Publication US 2021/0236564 A1, Aug. 5, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/745 (2015.01); A61P 25/20 (2006.01); A61K 35/747 (2015.01); A61K 45/06 (2006.01)

CPC A61K 35/745 (2013.01) [A61K 35/747 (2013.01); A61K 45/06 (2013.01); A61P 25/20 (2018.01)]

5 Claims

1. A method for treating a sleep disorder and/or improving sleep quality in a patient, comprising administering to the patient a composition (C) comprising:

(a) a bacterial strains mixture (M) comprising:

(a-i) a bacterium strain of the Lactobacillus fermentum species identified as the Lactobacillus fermentum LF16 DSM 26956 bacterium strain,

(a-ii) a bacterium strain of the Lactobacillus plantarum species selected from the group consisting of:

(a) a bacterium strain identified as the Lactobacillus plantarum LP01 LMG P-21021 bacterium strain, and

(b) a bacterium identified as the Lactobacillus plantarum LP02 LMG P-21020 bacterium strain,

(a-iii) a bacterium strain of the Lactobacillus rhamnosus species identified as the Lactobacillus rhamnosus LR06 DSM 21981 bacterium strain; and

(a-iv) a bacterium strain of the Bifidobacterium longum species identified as the Bifidobacterium longum BL04 DSM 23233 bacterium strain;

and, optionally,

(b) at least one technological additive and/or at least one pharmaceutical or food grade excipient.