US 11,678,667 B2
Agricultural compositions comprising remodeled nitrogen fixing microbes
Mark Reisinger, Berkeley, CA (US); Ernest Sanders, Berkeley, CA (US); Richard Broglie, Berkeley, CA (US); and Karsten Temme, Berkeley, CA (US)
Assigned to PIVOT BIO, INC., Berkeley, CA (US)
Filed by Pivot Bio, Inc., Berkeley, CA (US)
Filed on Jan. 14, 2022, as Appl. No. 17/576,106.
Application 17/576,106 is a continuation of application No. 17/254,175, previously published as PCT/US2019/039217, filed on Jun. 26, 2019.
Claims priority of provisional application 62/808,693, filed on Feb. 21, 2019.
Claims priority of provisional application 62/690,621, filed on Jun. 27, 2018.
Prior Publication US 2022/0151241 A1, May 19, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A01N 63/20 (2020.01)
CPC A01N 63/20 (2020.01) 126 Claims
OG exemplary drawing
 
1. A seed treatment composition, comprising:
a) a plurality of non-intergeneric remodeled bacteria; and
b) at least one compound of Formula (1) or a salt, solvate, or isomer thereof,
wherein Formula (1) comprises:

OG Complex Work Unit Chemistry
each E is independently O, S, or —NR7;
each G is independently C or N;
R1, R4, R5, and R6 are each independently H, amino, halo, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, —OR8, —C(O)R8,

OG Complex Work Unit Chemistry
or a lone electron pair, wherein

OG Complex Work Unit Chemistry
indicates a single bond;
R2 and R3 are each independently H, amino, halo, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted heterocycloalkyl, or a lone electron pair; or R2 and R3 together form a bond, or form a substituted or unsubstituted aryl; and
R7 and R8 are each independently H, amino, halo, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted cycloalkyl, or substituted or unsubstituted heterocycloalkyl.