CPC C12N 15/86 (2013.01) [C12N 5/0636 (2013.01); C12N 9/22 (2013.01); C12N 13/00 (2013.01); C12N 15/113 (2013.01); C12N 15/902 (2013.01); C12N 2310/20 (2017.05); C12N 2510/00 (2013.01); C12N 2800/80 (2013.01)] | 17 Claims |
1. A pair of PD-1-targeting TALE nuclease (TALEN) monomers comprising:
1) A TALEN monomer comprising the amino acid sequence of SEQ ID NO: 5 or SEQ ID NO: 9; and
2) A TALEN monomer comprising the amino acid sequence of SEQ ID NO: 6.
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