US 11,673,935 B2
Car T-cells recognizing cancer-specific IL 13Ra2
Irina V. Balyasnikova, Chicago, IL (US); Maciej S. Lesniak, Chicago, IL (US); and Stephen M. G. Gottschalk, Houston, TX (US)
Assigned to The University of Chicago, Chicago, IL (US); and Baylor College of Medicine, Houston, TX (US)
Filed by The University of Chicago, Chicago, IL (US); and Baylor College of Medicine, Houston, TX (US)
Filed on Nov. 6, 2019, as Appl. No. 16/675,861.
Application 16/675,861 is a continuation of application No. 15/545,950, abandoned, previously published as PCT/US2016/014985, filed on Jan. 26, 2016.
Claims priority of provisional application 62/245,771, filed on Oct. 23, 2015.
Claims priority of provisional application 62/107,980, filed on Jan. 26, 2015.
Prior Publication US 2020/0181227 A1, Jun. 11, 2020
Int. Cl. C07K 14/725 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01); A61P 35/00 (2006.01); C12N 15/79 (2006.01); A61K 39/00 (2006.01)
CPC C07K 14/7051 (2013.01) [A61P 35/00 (2018.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 14/7155 (2013.01); C07K 16/2866 (2013.01); C12N 15/79 (2013.01); A61K 2039/505 (2013.01); C07K 2317/41 (2013.01); C07K 2317/53 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01)] 5 Claims
 
1. A IL13Rα2-specific CAR comprising the amino acid sequence of SEQ ID NO: 53 or SEQ ID NO: 55.