US 11,673,905 B2
Topical composition comprising a small RNA tiger lily extract and method of cosmetic care to reduce skin signs of aging
Elodie Oger, Vallauris (FR); Rachel Chabert, Grasse (FR); Isabelle Imbert, Cannes (FR); Jean-Marie Botto, Valbonee (FR); Nouha Domloge, Opio (FR); Joel Mantelin, Cannes (FR); Nadine Pernodet, Huntington Station, NY (US); Kelly Dong, Merrick, NY (US); and Chia-Wen Chen, Eastchester, NY (US)
Assigned to ISP INVESTMENTS LLC, Wilmington, DE (US); and ELC MANAGEMENT LLC, Melville, NY (US)
Appl. No. 15/776,232
Filed by ELC Management LLC, Melville, NY (US); and ISP Investments LLC, Wilmington, DE (US)
PCT Filed Nov. 10, 2016, PCT No. PCT/US2016/061302
§ 371(c)(1), (2) Date May 15, 2018,
PCT Pub. No. WO2017/087245, PCT Pub. Date May 26, 2017.
Claims priority of application No. 1502361 (FR), filed on Nov. 17, 2015.
Prior Publication US 2020/0246252 A1, Aug. 6, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/44 (2006.01); C07H 1/08 (2006.01); A61K 8/60 (2006.01); C07H 21/02 (2006.01); A61Q 19/08 (2006.01); A61K 8/9789 (2017.01); C12N 15/10 (2006.01); A61Q 19/00 (2006.01); A61Q 17/04 (2006.01); A61K 8/9794 (2017.01)
CPC C07H 1/08 (2013.01) [A61K 8/44 (2013.01); A61K 8/606 (2013.01); A61K 8/9789 (2017.08); A61K 8/9794 (2017.08); A61Q 17/04 (2013.01); A61Q 19/00 (2013.01); A61Q 19/007 (2013.01); A61Q 19/08 (2013.01); C07H 21/02 (2013.01); C12N 15/1003 (2013.01); C12N 15/1017 (2013.01); A61K 2800/10 (2013.01); A61K 2800/30 (2013.01); A61K 2800/805 (2013.01)] 8 Claims
 
1. A cosmetic composition for topical application comprising an extract of bulb of Tiger lily (Lilium tigrinum) and a physiologically acceptable medium, wherein the said extract of Tiger lily has a dry weight from 10 to 12 g/kg, a sugar concentration from 4 to 8 g/Kg, a protein fragments concentration from 0.5 to 1.5 g/kg, a phenolic compounds concentration from 50 to 200 mg/kg and a content in RNA with a maximum length of 150 nucleotides concentration from 15 to 45 mg/kg.