US 11,672,963 B2
Device for transdermal delivery of active molecules, uses of the device and methods for producing the device and its components
Luca De Stefano, Naples (IT); Ilaria Rea, Caivano (IT); Principia Dardano, Ercolano (IT); and Luigi Nicolais, Ercolano (IT)
Assigned to Altergon SA, Lugano (CH)
Appl. No. 16/610,526
Filed by Altergon SA, Lugano (CH)
PCT Filed Apr. 6, 2018, PCT No. PCT/IB2018/052410
§ 371(c)(1), (2) Date Nov. 4, 2019,
PCT Pub. No. WO2018/203156, PCT Pub. Date Nov. 8, 2018.
Claims priority of application No. 102017000048421 (IT), filed on May 4, 2017.
Prior Publication US 2020/0086102 A1, Mar. 19, 2020
Int. Cl. A61M 37/00 (2006.01); A61K 9/00 (2006.01); A61N 5/06 (2006.01)
CPC A61M 37/0015 (2013.01) [A61K 9/0021 (2013.01); A61N 5/062 (2013.01); A61M 2037/0007 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0061 (2013.01); A61N 2005/063 (2013.01); A61N 2005/0659 (2013.01); A61N 2005/0662 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A device for the transdermal delivery of active molecules comprising:
a support element permeable to said active molecules;
a plurality of micro-needles permeable to said active molecules, said micro-needles protruding from a first surface of said support element and
a porous membrane configured to be loaded with said active molecules, said porous membrane lying on a second surface of said support element;
wherein said porous membrane is configured to be an optical Bragg mirror or a linear combination between optical Bragg mirrors or at least one single or coupled optical cavity, said optical Bragg mirror or said optical Bragg mirrors in said linear combination or said at least one single or coupled optical cavity having a periodic structure with the alternation of layers with low refractive index and layers with high refractive index,
the number of periods in said porous membrane being between 10 and 50.