US 11,672,884 B2
Silicone polyurea block copolymer coating compositions and methods
Kristin Taton, Little Canada, MN (US); Patrick Guire, Hopkins, MN (US); and Charles Leir, Ironton, MN (US)
Assigned to Innovative Surface Technologies, Inc., St. Paul, MN (US)
Appl. No. 16/771,380
Filed by Innovative Surface Technologies, Inc., St. Paul, MN (US)
PCT Filed Dec. 11, 2018, PCT No. PCT/US2018/064988
§ 371(c)(1), (2) Date Jun. 10, 2020,
PCT Pub. No. WO2019/118487, PCT Pub. Date Jun. 20, 2019.
Claims priority of provisional application 62/597,168, filed on Dec. 11, 2017.
Prior Publication US 2020/0405909 A1, Dec. 31, 2020
Int. Cl. A61L 31/10 (2006.01); A61L 27/34 (2006.01); C08G 18/61 (2006.01); C08G 18/64 (2006.01); C08G 18/73 (2006.01); C08G 18/75 (2006.01); C08G 18/77 (2006.01); C09D 183/10 (2006.01)
CPC A61L 27/34 (2013.01) [A61L 31/10 (2013.01); C08G 18/61 (2013.01); C08G 18/6423 (2013.01); C08G 18/73 (2013.01); C08G 18/757 (2013.01); C08G 18/778 (2013.01); C09D 183/10 (2013.01); C08G 2150/00 (2013.01)] 19 Claims
 
1. A medical device having a surface containing a passivating coating, the passivating coating comprising a silicone polyurea copolymer having a polymer backbone and comprising a reaction product of:
(a) a diamine composition comprising a polyethylene glycol diamine compound having a formula (I), (II), or a combination of (I) and (II):

OG Complex Work Unit Chemistry
wherein y is an integer in the range of 2 to 40, and x+z is an integer in the range of 1 to 8; or

OG Complex Work Unit Chemistry
wherein n is an integer in the range of 1 to 100;
(b) a monofunctional silicone isocyanate compound having a formula:

OG Complex Work Unit Chemistry
wherein D is an alkyl radical having 1 to 6 carbon atoms,
G is a bivalent alkyl radical having 1 to 6 carbon atoms,
each R is independently selected from a monovalent alkyl radical having about 1 to about 12 carbon atoms, a substituted alkyl radical having about 1 to about 12 carbon atoms, a phenyl radical and a substituted phenyl radical, and
m is an integer in the range of 15 to 300; and
(c) a diisocyanate compound, wherein the silicone polyurea copolymer comprises total isocyanate groups to total amine groups in a molar ratio of 1.5:1 to 1.05:1.