CPC A61K 49/0442 (2013.01) [A61K 49/0438 (2013.01); A61K 49/0476 (2013.01); A61K 49/0485 (2013.01); C08F 116/06 (2013.01); C08L 29/04 (2013.01); B82Y 5/00 (2013.01)] | 19 Claims |
1. A method of making a radiopaque hydrogel bead, comprising:
forming an activated hydrogel bead by reacting a preformed hydrogel bead with a carbonyldiimidazole or a carbodiimide; and
reacting functional groups on the activated hydrogel bead with an iodinated compound such at the iodinated compound is covalently coupled to the activated hydrogel bead, wherein the iodinated compound is an aromatic iodine containing compound.
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