CPC A61K 31/501 (2013.01) [A61K 31/502 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01)] | 9 Claims |
1. A compound according to Formula (IA), or salt thereof
wherein A is selected from the group consisting of:
wherein
u and v are each, independently, 0, 1, 2 or 3; and
each Raand Rb, are, independently, selected from cyano, halogen, hydroxy, C1-C4 alkyl, C2-C4alkenyl, C2-C4alkynyl, C1-C4alkoxy, C3-C7cycloalkyl, heterocyclyl, heteroaryl, heterocyclyl C1-C4alkyl, C1-C4alkyl aryl, C1-C4alkyl heterocyclyl, C1-C4alkyl heteroaryl, C1-C4alkoxy aryl, C1-C4alkoxy heterocyclyl, C1-C4alkoxy heteroaryl, and C1-C4alkoxy substituted with hydroxy, C1-C4 alkoxy, amino and mono-and di-C1-C4alkylamino; and
B is selected from the group consisting of:
wherein X is O or N(Me) or NH; and
R17 is hydrogen or methyl.
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