	US 11,672,790 B2
	Methods of managing conditioned fear with neurokinin receptor antagonists
Kerry J. Ressler, Atlanta, GA (US); and Raul Andreo Gali, Atlanta, GA (US)
Assigned to Emory University, Atlanta, GA (US)
Filed by Emory University, Atlanta, GA (US)
Filed on Nov. 6, 2019, as Appl. No. 16/676,030.
Application 16/676,030 is a continuation of application No. 16/369,594, filed on Mar. 29, 2019, abandoned.
Application 16/369,594 is a continuation of application No. 15/320,952, granted, now 10,314,835, issued on Jun. 11, 2019, previously published as PCT/US2015/037629, filed on Jun. 25, 2015.
Claims priority of provisional application 62/016,683, filed on Jun. 25, 2014.
Prior Publication US 2020/0171021 A1, Jun. 4, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/4545 (2006.01); A61K 45/06 (2006.01)

CPC A61K 31/4545 (2013.01) [A61K 45/06 (2013.01)]

4 Claims

1. A method of reducing the risk of developing symptoms of PTSD in a subject that is at high-risk of developing PTSD, wherein said method comprises:

administering an effective amount of osanetant to the subject within 24 hours of experiencing a trauma that is a high-risk event for the development of PTSD;

wherein a high-risk event is selected from a group consisting of: a sexual assault and combat; and

wherein the administration begins prior to the subject developing a symptom of PTSD and after experiencing the high-risk event.