US 11,672,695 B2
Central nervous system localized hypothermia apparatus and methods
Adam William Martinez, Kennesaw, GA (US); Rachel Candace Howell, Marietta, GA (US); Emily Renee Croft, Mableton, GA (US); Jeremy Gura, Peachtree City, GA (US); and Alejandro A. Aviles, Kennesaw, GA (US)
Assigned to ARTIVION, INC., Atlanta, GA (US)
Filed by Artivion, Inc., Kennesaw, GA (US)
Filed on Mar. 22, 2019, as Appl. No. 16/361,566.
Claims priority of provisional application 62/646,539, filed on Mar. 22, 2018.
Prior Publication US 2019/0290481 A1, Sep. 26, 2019
Int. Cl. A61F 7/12 (2006.01); A61M 25/00 (2006.01); A61M 27/00 (2006.01); A61M 39/22 (2006.01); A61F 7/00 (2006.01)
CPC A61F 7/12 (2013.01) [A61M 25/007 (2013.01); A61M 25/0026 (2013.01); A61M 27/006 (2013.01); A61M 39/22 (2013.01); A61F 2007/0056 (2013.01); A61F 2007/126 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/366 (2013.01); A61M 2205/3606 (2013.01); A61M 2205/3673 (2013.01); A61M 2210/1003 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A spinal cooling and drainage apparatus, comprising:
a drainage and cooling catheter assembly adapted for intrathecal insertion into a patient, the drainage and cooling catheter assembly comprising:
a working end portion;
an insertion portion having a maximum cross-sectional dimension of about 5 Fr;
a drainage catheter having a proximal end, a distal end open to cerebrospinal fluid flow, and a central lumen passing therebetween; and
a cooling catheter having a proximal end, a closed distal end, a first interior lumen, and a second interior lumen in fluid communication with the first interior lumen near the closed distal end of the cooling catheter, the cooling catheter configured to be passed through the central lumen of the drainage catheter such that there is a gap permitting cerebrospinal fluid flow between an inner wall of the central lumen of the drainage catheter and an outer wall of the cooling catheter; and
a console, comprising:
a drainage pump;
a cerebrospinal fluid collection reservoir fluidically coupled to the drainage and cooling catheter assembly and configured to collect cerebrospinal fluid;
a drainage control system operatively connected to the drainage pump and configured to control a rate of drainage of cerebrospinal fluid from a patient, wherein the drainage control system comprises a non-contact measuring system configured to monitor a volume of cerebrospinal fluid collected inside the cerebrospinal fluid collection reservoir;
a coolant pump coupled to the drainage and cooling catheter assembly and configured to circulate a coolant between the drainage and cooling catheter assembly and the console; and
a chiller assembly comprising a thermoelectric cooling unit;
wherein the drainage catheter is adapted to be fluidically coupled to the cerebrospinal fluid collection reservoir; and
wherein the cooling catheter is adapted to be fluidically coupled to the chiller assembly for accepting and returning the coolant thereto.