US 11,672,651 B2
Artificial valved conduits for cardiac reconstructive procedures and methods for their production
Masahiro Yoshida, Pittsburgh, PA (US); C. Douglas Bernstein, Pittsburgh, PA (US); Onur Dur, San Ramon, CA (US); and Kerem Pekkan, Pittsburgh, PA (US)
Assigned to CARNEGIE MELLON UNIVERSITY, Pittsburgh, PA (US); and UNIVERSITY OF PITTSBURGH, Pittsburgh, PA (US)
Filed by CARNEGIE MELLON UNIVERSITY, Pittsburgh, PA (US); and UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, Pittsburgh, PA (US)
Filed on Feb. 7, 2020, as Appl. No. 16/784,775.
Application 16/784,775 is a continuation of application No. 15/413,571, filed on Jan. 24, 2017, granted, now 10,624,737.
Application 15/413,571 is a continuation of application No. 14/235,578, granted, now 9,585,746, issued on Mar. 7, 2017, previously published as PCT/US2012/048902, filed on Jul. 30, 2012.
Claims priority of provisional application 61/633,634, filed on Feb. 14, 2012.
Claims priority of provisional application 61/628,209, filed on Oct. 26, 2011.
Claims priority of provisional application 61/574,254, filed on Jul. 29, 2011.
Prior Publication US 2020/0170790 A1, Jun. 4, 2020
Int. Cl. A61F 2/24 (2006.01); A61F 2/06 (2013.01); A61L 27/16 (2006.01); A61L 33/00 (2006.01); A61L 27/24 (2006.01); A61L 27/36 (2006.01); A61L 27/58 (2006.01)
CPC A61F 2/2412 (2013.01) [A61F 2/06 (2013.01); A61F 2/2403 (2013.01); A61F 2/2409 (2013.01); A61F 2/2415 (2013.01); A61F 2/2475 (2013.01); A61L 27/16 (2013.01); A61L 27/24 (2013.01); A61L 27/367 (2013.01); A61L 27/58 (2013.01); A61L 33/0011 (2013.01); A61F 2002/068 (2013.01); A61F 2250/0037 (2013.01); A61F 2250/0067 (2013.01); A61F 2250/0082 (2013.01); A61L 2430/20 (2013.01); Y10T 29/49412 (2015.01)] 12 Claims
OG exemplary drawing
 
1. A valve structure comprising:
a conduit having an inner conduit surface; and
a leaflet structure having an open state and a closed state, the leaflet structure comprising:
a plurality of valve leaflets, each valve leaflet comprising a sinus structure having a sinus edge and a fan structure having a fan edge;
wherein at least a portion of the sinus edge is affixed to a portion of the inner conduit surface; and
wherein, when the leaflet structure is in the closed state, the fan edges of the plurality of valve leaflets are mutually disposed to form a plurality of valve gaps between at least a portion of the fan edges and the inner conduit surface; and
wherein, when the leaflet structure is in the open state, at least one fan structure is disposed to form a gap between the fan edge of the at least one fan structure and the inner conduit surface.