US 11,668,653 B2
Raman-based immunoassay systems and methods
Patrick Treado, Pittsburgh, PA (US); Shona Stewart, Pittsburgh, PA (US); Aaron Smith, Pittsburgh, PA (US); and Heather Gomer, Sewickley, PA (US)
Assigned to CHEMIMAGE CORPORATION, Pittsburgh, PA (US)
Appl. No. 15/776,649
Filed by ChemImage Corporation, Pittsburgh, PA (US)
PCT Filed Nov. 16, 2016, PCT No. PCT/US2016/062361
§ 371(c)(1), (2) Date May 16, 2018,
PCT Pub. No. WO2017/087574, PCT Pub. Date May 26, 2017.
Claims priority of provisional application 62/255,804, filed on Nov. 16, 2015.
Prior Publication US 2018/0348136 A1, Dec. 6, 2018
Int. Cl. G01N 21/65 (2006.01); G01J 3/44 (2006.01); G01N 21/17 (2006.01); G01J 3/02 (2006.01); G01J 3/28 (2006.01); G16H 50/20 (2018.01); G01N 33/53 (2006.01)
CPC G01N 21/65 (2013.01) [G01J 3/0218 (2013.01); G01J 3/0291 (2013.01); G01J 3/2823 (2013.01); G01J 3/44 (2013.01); G01N 21/17 (2013.01); G01N 33/53 (2013.01); G16H 50/20 (2018.01); G01N 2201/0833 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01); G01N 2800/60 (2013.01)] 51 Claims
OG exemplary drawing
 
1. A system comprising:
an illumination source configured to illuminate a biological sample and generate a plurality of interacted photons;
a detector configured to detect the plurality of interacted photons and generate at least one Raman data set; and
a processor configured to fuse the at least one Raman data set with at least one biomarker data set to identify one or more of a disease and a disease state.