	US 11,667,705 B2
	IL-17A binding proteins
Bryan Edwards, Cambridge (GB); Ulla Lashmar, Cambridge (GB); Brian McGuinness, Cambridge (GB); Mike Romanos, Cambridge (GB); Thomas Sandal, Cambridge (GB); and Yumin Teng, Cambridge (GB)
Assigned to Crescendo Biologics Limited, Cambridge (GB)
Filed by Crescendo Biologics Limited, Cambridge (GB)
Filed on Apr. 8, 2020, as Appl. No. 16/843,474.
Application 16/843,474 is a continuation of application No. 15/541,889, granted, now 10,654,924, previously published as PCT/GB2016/005007, filed on Jan. 12, 2016.
Claims priority of application No. 1500463 (GB), filed on Jan. 12, 2015.
Prior Publication US 2020/0347127 A1, Nov. 5, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 16/24 (2006.01); A61K 39/395 (2006.01); A01K 67/027 (2006.01); C12N 15/63 (2006.01); A61P 37/02 (2006.01); A61P 31/00 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01)

CPC C07K 16/244 (2013.01) [A01K 67/0278 (2013.01); A61K 39/3955 (2013.01); A61P 31/00 (2018.01); A61P 37/02 (2018.01); A61P 37/06 (2018.01); A61P 37/08 (2018.01); C12N 15/63 (2013.01); G01N 33/6869 (2013.01); A01K 2217/072 (2013.01); A01K 2217/075 (2013.01); A01K 2217/15 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); G01N 2333/54 (2013.01)]

7 Claims

1. A binding molecule comprising a single domain antibody that binds human IL-17A, said single domain antibody comprising a human heavy chain variable immunoglobulin domain (V_H) that comprises a CDR1, a CDR2, and a CDR3 sequence,

wherein said CDR1 sequence comprises the amino acid sequence of SEQ ID NO. 5;

wherein said CDR2 sequence comprises the amino acid sequence of SEQ ID NO. 6; and

wherein said CDR3 sequence comprises the amino acid sequence of SEQ ID NO. 7.