US 11,667,665 B2
Aqueous suspension compositions, formulations, and water dispersible dry compositions comprising 16alpha-bromo-3beta-hydroxy-5alpha-androstan-17-ketone and hydrates, derivatives, and analogs thereof
Yu Ge, San Diego, CA (US)
Assigned to SD Chem, Inc., San Diego, CA (US)
Filed by SD Chem, Inc., San Diego, CA (US)
Filed on Nov. 13, 2020, as Appl. No. 17/98,314.
Application 17/098,314 is a continuation of application No. 16/267,815, filed on Feb. 5, 2019, granted, now 10,836,788.
Prior Publication US 2021/0061847 A1, Mar. 4, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07J 1/00 (2006.01); A61K 9/00 (2006.01); A61K 31/5685 (2006.01); A61P 1/00 (2006.01); A61P 31/06 (2006.01); A61P 37/06 (2006.01); A61P 3/10 (2006.01); A61P 35/00 (2006.01); A61K 9/19 (2006.01); A61K 47/34 (2017.01); A61K 47/38 (2006.01); A61P 11/06 (2006.01)
CPC C07J 1/0011 (2013.01) [A61K 9/0019 (2013.01); A61K 9/19 (2013.01); A61K 31/5685 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01); A61P 1/00 (2018.01); A61P 3/10 (2018.01); A61P 11/06 (2018.01); A61P 31/06 (2018.01); A61P 35/00 (2018.01); A61P 37/06 (2018.01)] 20 Claims
 
1. A composition, comprising
at least 30% w/w water based on total weight of the composition, and
a compound of Formula I:

OG Complex Work Unit Chemistry
wherein n is 0 to 4;
the solvate is H2O, C1-4—OH, C1-4—OH, C1-4—COOH, C1-4—COOC1-4, tetrahydrofuran, 1,4-dioxane, (CH3)2O, (C2H5)2O, HC(O)N(CH3)2, (CH3)2SO, or a combination thereof;
X is F, Cl, Br, or I;
R is a protecting group,
wherein the compound is in form of particles stabilized as an aqueous suspension in the water.