US 11,667,630 B2
Nitrogen-containing 6-membered cyclic compound
Daisuke Shikanai, Tokyo (JP); Noriko Ishiguro, Tokyo (JP); and Osamu Omori, Tokyo (JP)
Assigned to ASAHI KASEI PHARMA CORPORATION, Tokyo (JP)
Filed by Asahi Kasei Pharma Corporation, Tokyo (JP)
Filed on Mar. 4, 2021, as Appl. No. 17/192,614.
Application 17/192,614 is a continuation of application No. 16/333,510, granted, now 10,988,468, previously published as PCT/JP2018/047450, filed on Dec. 25, 2018.
Claims priority of application No. 2017-248173 (JP), filed on Dec. 25, 2017.
Prior Publication US 2021/0188837 A1, Jun. 24, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 417/14 (2006.01); A61P 41/00 (2006.01); A61P 19/00 (2006.01)
CPC C07D 417/14 (2013.01) [A61P 19/00 (2018.01); A61P 41/00 (2018.01)] 19 Claims
 
1. A compound represented by the following general formula (1):

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[wherein, in the formula (1),
R1 represents —H, or halogen;
Ar1 represents any substituent selected from the group G1, which may be substituted with 1 to 3 of the same or different substituents selected from the group consisting of —F and methyl (provided that

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 are excluded),
wherein the group G1 is a group consisting of

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(a and b represent binding direction);
Ar2 represents any substituent selected from the group G2, which may be substituted with 1 to 3 of the same or different substituents selected from the group consisting of cyano, —Cl, methyl, methoxy, and phenyl (provided that

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 are excluded),
wherein the group G2 is a group consisting of phenyl, thienyl, furyl, and thiazolyl; and
* represents an asymmetric carbon],
or a salt thereof.