	US 11,667,610 B2
	Method for preparing Macitentan and intermediate compound thereof
Qiang Jia, Taizhou (CN); Chi Ma, Taizhou (CN); Zhengwei Yang, Zhejiang (CN); and Jinjin Yang, Taizhou (CN)
Assigned to Seasons Biotechnology (Taizhou) Co., Ltd., Taizhou (CN)
Filed by Seasons Biotechnology (Taizhou) Co., Ltd., Taizhou (CN)
Filed on Jun. 29, 2022, as Appl. No. 17/852,847.
Application 17/852,847 is a division of application No. 16/336,504, previously published as PCT/CN2017/102452, filed on Sep. 20, 2017.
Claims priority of application No. 201610879475.1 (CN), filed on Sep. 28, 2016.
Prior Publication US 2022/0348547 A1, Nov. 3, 2022
Int. Cl. C07D 239/47 (2006.01)

CPC C07D 239/47 (2013.01)

8 Claims

1. A method for preparing compound II, wherein the preparation method comprising: reacting compound III with ethylene glycol in the presence of cesium carbonate to obtain compound II