CPC A61K 39/155 (2013.01) [A61K 9/08 (2013.01); A61K 38/13 (2013.01); A61P 31/14 (2018.01); C12N 2760/18522 (2013.01); C12N 2760/18534 (2013.01); C12N 2760/18571 (2013.01)] | 12 Claims |
1. An immune composition, comprising (i) a modified respiratory syncytial virus (RSV) G polypeptide or a nucleic acid encoding the modified RSV G polypeptide, and (ii) an immune regulator;
wherein the modified RSV polypeptide lacks a transmembrane domain as compared with the wild-type counterpart,
wherein the modified RSV G polypeptide comprises the amino acid sequence of any one of SEQ ID NOs:1-4;
wherein the immune regulator is cyclosporin A; and
wherein the immune composition further comprises a non-ionic surfactant, which comprises polyethylene glycol (15)-hydroxystearate.
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