US 11,666,609 B2
Methods of treating dog urinary tract infections
JoEllen L. Westropp, Davis, CA (US); Anthony J. Schaeffer, Chicago, IL (US); and David J. Klumpp, Chicago, IL (US)
Assigned to The Regents of the University of California, Oakland, CA (US); and Northwestern University, Evanston, IL (US)
Appl. No. 16/769,962
Filed by The Regents of the University of California, Oakland, CA (US); and Northwestern University, Evanston, IL (US)
PCT Filed Dec. 4, 2018, PCT No. PCT/US2018/063867
§ 371(c)(1), (2) Date Jun. 4, 2020,
PCT Pub. No. WO2019/113086, PCT Pub. Date Jun. 13, 2019.
Claims priority of provisional application 62/594,917, filed on Dec. 5, 2017.
Prior Publication US 2020/0397835 A1, Dec. 24, 2020
Int. Cl. A61K 35/741 (2015.01); A61K 9/00 (2006.01)
CPC A61K 35/741 (2013.01) [A61K 9/0034 (2013.01)] 9 Claims
 
1. A method of treating a recurrent clinical urinary tract infection (UTI) in a dog having a history of UTIs, the method comprising administering via one or more intravesicular instillations into the bladder of the dog a sufficient number of asymptomatic bacteriuria (ASB) E. coli 2-12 CFUs, wherein ASB E. coli 2-12 is deposited with the American Type Culture Collection under Accession Number PTA-124177, and wherein the dog does not experience a recurrent UTI within 2 months of receiving a first instillation of ASB E. coli 2-12.