US 11,666,335 B2
Surgical stapler with end effector coating
Thomas W. Huitema, Cincinnati, OH (US); Xintian Ming, Bridgewater, NJ (US); Tamara S. Widenhouse, Clarksville, OH (US); and Frederick E. Shelton, IV, Hillsboro, OH (US)
Assigned to Cilag GmbH International, Zug (CH)
Filed by Cilag GmbH International, Zug (CH)
Filed on Jan. 28, 2021, as Appl. No. 17/161,069.
Application 17/161,069 is a continuation of application No. 15/621,551, filed on Jun. 13, 2017, granted, now 10,939,911.
Prior Publication US 2021/0177417 A1, Jun. 17, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 17/072 (2006.01); A61L 31/16 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); A61L 31/06 (2006.01); A61B 17/064 (2006.01); A61B 17/00 (2006.01); A61B 17/115 (2006.01)
CPC A61B 17/07292 (2013.01) [A61B 17/0644 (2013.01); A61B 17/072 (2013.01); A61B 17/07207 (2013.01); A61L 31/06 (2013.01); A61L 31/10 (2013.01); A61L 31/14 (2013.01); A61L 31/16 (2013.01); A61B 17/064 (2013.01); A61B 17/1155 (2013.01); A61B 2017/00004 (2013.01); A61B 2017/00464 (2013.01); A61B 2017/00477 (2013.01); A61B 2017/00526 (2013.01); A61B 2017/00884 (2013.01); A61B 2017/00893 (2013.01); A61B 2017/07257 (2013.01); A61B 2017/07271 (2013.01); A61B 2017/07278 (2013.01); A61B 2017/07285 (2013.01); A61L 2420/02 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A staple cartridge assembly for use with a surgical stapler, comprising:
a cartridge body having a plurality of staple cavities and a plurality of staples, each staple being disposed within one of the plurality of staple cavities and configured to be deployed into tissue; and
a mixture disposed on at least a portion of the outer surface of the plurality of staple cavities and on at least a portion of the outer surface of the plurality of staples, the mixture comprising at least one matrix metalloproteinase (MMP) inhibitor and an adhesion coating comprising an absorbable polymer and an absorbable lubricant, the adhesion coating being configured to adhere the at least one MMP inhibitor to the outer surface, and the mixture being configured to be released from the outer surface upon deployment of the plurality of staples into tissue.