US 11,656,208 B2
Multi-injection mode valve module
Sylvain Cormier, Mendon, MA (US); Richard W. Andrews, Rehoboth, MA (US); and Peyton C. Beals, Wrentham, MA (US)
Assigned to WATERS TECHNOLOGIES CORPORATION, Milford, MA (US)
Filed by Waters Technologies Corporation, Milford, MA (US)
Filed on Mar. 19, 2021, as Appl. No. 17/206,994.
Application 17/206,994 is a continuation of application No. 15/559,276, granted, now 10,955,391, previously published as PCT/US2016/018218, filed on Feb. 17, 2016.
Claims priority of provisional application 62/140,615, filed on Mar. 31, 2015.
Prior Publication US 2021/0208114 A1, Jul. 8, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 30/32 (2006.01); G01N 30/34 (2006.01); G01N 30/20 (2006.01); G01N 30/24 (2006.01); G01N 30/22 (2006.01); G01N 30/86 (2006.01); G01N 30/88 (2006.01); G01N 30/02 (2006.01)
CPC G01N 30/32 (2013.01) [G01N 30/20 (2013.01); G01N 30/22 (2013.01); G01N 30/24 (2013.01); G01N 30/34 (2013.01); G01N 30/8665 (2013.01); G01N 30/88 (2013.01); G01N 2030/027 (2013.01); G01N 2030/201 (2013.01); G01N 2030/202 (2013.01); G01N 2030/328 (2013.01); G01N 2030/347 (2013.01); G01N 2030/8804 (2013.01); G01N 2030/889 (2013.01); G01N 2030/8881 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A chromatography system comprising:
a gradient delay volume defined as an overall fluid volume between where gradient is proportioned until an inlet of a chromatography column;
a pump pumping a flow of gradient; and
at least one valve located downstream from the pump, the at least one valve having a plurality of ports including an inlet port that receives the flow of gradient from the pump and an outlet port through which the flow of gradient exits the at least one valve, the at least one valve having at least two positions, wherein a first position of the at least two positions of the at least one valve increases the gradient delay volume of the chromatography system relative to when the at least one valve is in a second position.