CPC A61N 5/10 (2013.01) [A61B 17/3205 (2013.01); A61K 31/4439 (2013.01); A61K 31/513 (2013.01); A61K 35/00 (2013.01); A61N 5/062 (2013.01); A61N 5/0616 (2013.01); A61P 17/02 (2018.01); A61P 35/00 (2018.01); A61B 18/0218 (2013.01); A61B 2017/00761 (2013.01); A61N 5/067 (2021.08); A61N 2005/0663 (2013.01)] | 16 Claims |
1. A method for treating clinical or pre-clinical skin damage in a skin field of a subject, wherein the skin field has been allocated a global score of at least 1 by a process comprising the steps of:
(i) assessing the skin field for:
(a) a small area affected with few or thin keratoses;
(b) patchy involvement in the zone, moderately thick keratosis, or patchy involvement in the zone with moderately thick keratoses;
(c) extensive involvement of the zone, numerous thicker keratosis, or extensive involvement of the zone with numerous thicker keratoses;
(d) extensive involvement of the zone with (A) numerous thicker keratosis with cutaneous horn; and/or (B) confluent (i.e. continuous) keratoses, or
(e) near complete involvement of the zone with numerous thicker keratosis, wherein the assessment does not involve assessment of erythema in the skin field; and
(ii) assigning the skin field a global score based on the results of assessment (i) wherein the global score assigned is 1 for (a), 2 for (b), 3 for (c) and 4 for (d) or (e);
the method for treating the clinical or pre-clinical skin damage comprising:
treating the skin field with field radiotherapy when the skin field is assigned a global score of 4;
treating the skin field with field radiotherapy and/or applying a topical treatment when the skin field is assigned a global score of 3;
A. treating the skin field by applying a topical treatment and/or lesional therapy when the skin field is assigned a global score of 2; and
B. treating the skin field with lesional therapy when the skin field is assigned a global score of 1.
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