CPC A61K 31/519 (2013.01) [A61K 31/4045 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01)] | 17 Claims |
1. A method for killing bacterial persister cells and/or dormant “viable but non-culturable” (VBNC) cells in a bacterial population, the method comprising administering to the bacterial population an effective amount of [(5-nitro-3-phenyl-1H-indol-2-yl)methyl]amine having the formula:
or a salt thereof, [(5-nitro-3-phenyl-1H-indol-2-yl)methyl]amine hydrochloride (NPIMA), having the formula:
and wherein the bacterial persister cells and/or VBNC comprise bacteria selected from Escherichia spp., Staphylococcus spp., and Pseudomonas spp.
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