CPC A61K 9/0019 (2013.01) [A61K 38/20 (2013.01); C07K 14/54 (2013.01)] | 19 Claims |
1. A method of treating a disease in a human individual, comprising intravenously administering to the human individual an effective amount of an IL-22 dimer, wherein the amount of the IL-22 dimer is about 2 μg/kg to about 200 μg/kg, wherein the IL-22 dimer comprises two monomeric subunits, wherein each monomeric subunit comprises an IL-22 domain and a dimerization domain, wherein the dimerization domain comprises the CH2 and CH3 domains of human IgG, and wherein the disease is liver disease, Parkinson's disease, or stroke.
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