US 11,967,496 B2
High resolution imaging apparatus and method
Paul Corkum, Ottawa (CA); and Alexander V. Loboda, Thornhill (CA)
Assigned to Standard BioTools Canada Inc.; and University of Ottawa, Markham (CA)
Filed by Fluidigm Canada Inc., Markham (CA); and University of Ottawa, Ottawa (CA)
Filed on Jan. 21, 2022, as Appl. No. 17/580,917.
Application 17/580,917 is a continuation of application No. 17/253,538, granted, now 11,264,221, previously published as PCT/US2019/037644, filed on Jun. 18, 2019.
Claims priority of provisional application 62/792,759, filed on Jan. 15, 2019.
Claims priority of provisional application 62/686,341, filed on Jun. 18, 2018.
Prior Publication US 2022/0223398 A1, Jul. 14, 2022
Int. Cl. H01J 49/04 (2006.01); G01N 33/68 (2006.01); G02B 21/33 (2006.01); H01J 37/20 (2006.01); H01J 37/28 (2006.01); H01J 49/00 (2006.01); H01J 49/02 (2006.01); H01J 49/06 (2006.01); H01J 49/10 (2006.01); H01J 49/14 (2006.01); H01J 49/16 (2006.01); H01J 49/40 (2006.01)
CPC H01J 49/0463 (2013.01) [G01N 33/6848 (2013.01); G01N 33/6851 (2013.01); G02B 21/33 (2013.01); H01J 37/20 (2013.01); H01J 37/28 (2013.01); H01J 49/0004 (2013.01); H01J 49/0031 (2013.01); H01J 49/025 (2013.01); H01J 49/0418 (2013.01); H01J 49/067 (2013.01); H01J 49/105 (2013.01); H01J 49/142 (2013.01); H01J 49/161 (2013.01); H01J 49/164 (2013.01); H01J 49/40 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus for analyzing a biological sample comprising:
a sample stage;
a source of charged particles, the source of charged particles configured to pass a beam of charged particles to a location on the sample stage; and
a first laser source and first focusing optics configured to direct a laser beam emitted by the first laser source towards the sample stage,
wherein the source of charged particles, the first laser source, and the first focusing optics are configured such that the beam of charged particles and the laser beam are directed towards opposite sides of the sample stage.