US 11,965,950 B2
Slice ordering for MB-EPI ASL imaging
Xiufeng Li, Shoreview, MN (US); Gregory J. Metzger, Lake Elmo, MN (US); Essa Yacoub, Hudson, WI (US); Kamil Ugurbil, Minneapolis, MN (US); and Dingxin Wang, Apple Valley, MN (US)
Assigned to Siemens Healthineers AG, Forchheim (DE); and Regents of the University of Minnesota, Minneapolis, MN (US)
Filed by Siemens Healthineers AG, Forchheim (DE); and Regents of the University of Minnesota, Minneapolis, MN (US)
Filed on Jul. 29, 2019, as Appl. No. 16/524,254.
Claims priority of provisional application 62/837,784, filed on Apr. 24, 2019.
Prior Publication US 2020/0341099 A1, Oct. 29, 2020
Int. Cl. G01R 33/563 (2006.01); G01R 33/483 (2006.01); G01R 33/561 (2006.01)
CPC G01R 33/56366 (2013.01) [G01R 33/4835 (2013.01); G01R 33/5611 (2013.01); G01R 33/5616 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A method for generating a perfusion weighted image using arterial spin labeling (ASL) with segmented acquisitions, the method comprising:
dividing an anatomical area of interest into a plurality of slice bands, each of the plurality of slice bands comprising a sub-area of the anatomical area and including a predetermined number of respective slices, each of the respective slices of a given slice band comprising a portion of the sub-area of the given slice band;
performing a multi-band (MB) echo planar imaging (EPI) acquisition process using a magnetic resonance imaging (MRI) system to acquire a control image dataset representative of the plurality of slice bands, wherein each slice band is scanned using a central-to-peripheral slice acquisition order in which one or more respective slices within the center of the slice band is scanned prior to scanning the respective slices at the periphery of the slice band;
performing an ASL preparation process, using the MRI system to magnetically label protons in arterial blood water in an area upstream from the anatomical area of interest;
following a post-labeling delay time period, performing the MB EPI acquisition process to a labeled image dataset corresponding to the slices using the central-to-peripheral slice acquisition order; and
generating a perfusion weighted image of the anatomical area by subtracting the labeled image dataset from the control image dataset.