US 11,965,898 B2
Automatic nucleic acid detection system and method thereof
Yung-Hsiang Lin, Taipei (TW); Cheng-Hong Hsieh, Taipei (TW); Ciao-Ting Chen, Taipei (TW); and Tsung-Cheng Chen, Taipei (TW)
Assigned to TCI GENE INC, Taipei (TW); and TCI CO., LTD, Taipei (TW)
Filed by TCI Co., Ltd., Taipei (TW); and TCI GENE INC, Taipei (TW)
Filed on Jul. 23, 2020, as Appl. No. 16/936,810.
Claims priority of provisional application 63/000,667, filed on Mar. 27, 2020.
Claims priority of application No. 109119920 (TW), filed on Jun. 12, 2020.
Prior Publication US 2021/0302448 A1, Sep. 30, 2021
Int. Cl. G01N 35/10 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 35/00 (2006.01)
CPC G01N 35/00613 (2013.01) [B01L 3/5021 (2013.01); B01L 3/50825 (2013.01); B01L 3/50857 (2013.01); B01L 3/52 (2013.01); B01L 3/5453 (2013.01); B01L 3/5457 (2013.01); B01L 7/525 (2013.01); G01N 35/10 (2013.01); B01L 2200/10 (2013.01); B01L 2200/143 (2013.01); B01L 2200/16 (2013.01); B01L 2300/021 (2013.01); B01L 2300/04 (2013.01); B01L 2300/0663 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An automatic nucleic acid detection system, comprising:
a nucleic acid extraction machine platform, wherein a nucleic acid extraction device is disposed on the nucleic acid extraction machine platform;
a nucleic acid distribution machine platform, wherein a second robotic arm is disposed on the nucleic acid distribution machine platform;
a nucleic acid detection machine platform, wherein a nucleic acid detection device is disposed on the nucleic acid detection machine platform; and
an automatic control subsystem, comprising a computer device and the second robotic arm and being connected with the nucleic acid extraction machine platform, the nucleic acid distribution machine platform and the nucleic acid detection machine platform,
wherein the nucleic acid extraction device is configured to perform, on the nucleic acid extraction machine platform, nucleic acid extraction on one or a plurality of specimens in a sample tray to generate one or a plurality of corresponding nucleic acids in the sample tray;
wherein the computer device is configured to control the second robotic arm to perform, on the nucleic acid distribution machine platform, nucleic acid distribution from one sample tray having a fewer number of holes to one detection tray having a greater number of holes in a way that nucleic acid in each hole of the one sample tray and a first reagent are distributed into a plurality of holes of the one detection tray; and
wherein the nucleic acid detection device is configured to perform, on the nucleic acid detection machine platform, nucleic acid detection on the one detection tray.