US 11,964,107 B2
Nitric oxide administration in high frequency oscillatory ventilation
Thierry Boulanger, Philadelphia, PA (US)
Assigned to L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude, Paris (FR)
Filed by L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude, Paris (FR)
Filed on Apr. 2, 2021, as Appl. No. 17/220,992.
Claims priority of provisional application 63/004,157, filed on Apr. 2, 2020.
Prior Publication US 2021/0308411 A1, Oct. 7, 2021
Int. Cl. A61M 16/00 (2006.01); A61M 16/12 (2006.01); A61M 16/20 (2006.01)
CPC A61M 16/12 (2013.01) [A61M 16/0003 (2014.02); A61M 16/20 (2013.01); A61M 2016/0027 (2013.01); A61M 2016/003 (2013.01); A61M 2202/0275 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A gas delivery system (1, 2) for providing gaseous Nitric Oxide (NO) to a patient comprising:
a medical ventilator (2) providing a respiratory gas to a patient breathing circuit (3) comprising an inspiratory limb (31), said inspiratory limb (31) comprising a respiratory gas flow sensor (100), said respiratory gas flow sensor (100) having a differential pressure sensor (104), and an NO injection module (110), and
a NO delivery device (1) for providing a NO-containing gas to the NO injection module (110) of the inspiratory limb (31), said NO delivery device (1) comprising a control unit (130), wherein:
the respiratory gas flow sensor (100) cooperates with the differential pressure sensor (104) for determining at least one differential pressure value and providing said at least one differential pressure value to the control unit (130), and
the control unit (130) is configured for:
a) processing the at least one differential pressure value provided by the differential pressure sensor (104) for determining an actual flow of respiratory gas in the inspiratory limb (31), and
b) using the actual flow of respiratory gas determined in step a) for determining an amount of NO-containing gas to be provided by the NO delivery device (1) to the NO injection module (110), said NO injection module (110) being configured for delivering said NO-containing gas in the inspiratory limb (31) of the patient breathing circuit (3),
wherein the NO injection module (110) comprises an NO injection line (111) comprising a solenoid valve (113) controlled by the control unit (130), and wherein the NO injection line (111) further comprises a calibrated orifice (112) arranged downstream of the solenoid valve (113).