US 11,964,040 B2
Oral health composition comprising purified biosurfactants and/or their derivatives
Sean Farmer, North Miami Beach, FL (US); and Ken Alibek, Solon, OH (US)
Assigned to Locus Solutions IPCo, LLC, Solon, OH (US)
Appl. No. 16/760,635
Filed by Locus Solutions IPCo, LLC, Solon, OH (US)
PCT Filed Dec. 16, 2018, PCT No. PCT/US2018/065894
§ 371(c)(1), (2) Date Apr. 30, 2020,
PCT Pub. No. WO2019/133313, PCT Pub. Date Jul. 4, 2019.
Claims priority of provisional application 62/611,268, filed on Dec. 28, 2017.
Prior Publication US 2020/0345610 A1, Nov. 5, 2020
Int. Cl. A61K 8/64 (2006.01); A61K 8/60 (2006.01); A61K 8/69 (2006.01); A61Q 11/00 (2006.01)
CPC A61K 8/64 (2013.01) [A61K 8/60 (2013.01); A61K 8/69 (2013.01); A61Q 11/00 (2013.01)] 4 Claims
 
1. A method for treating a gum disease, gingivitis and/or periodontal disease in a subject's oral cavity, the method comprising applying a composition consisting essentially of a purified sophorolipid component and a mannosylerythritol lipid to microbial biofilm that is present on a surface of the subject's oral cavity in need of said treatment, wherein said sophorolipid component comprises at least 70% by weight of an acidic form sophorolipid, and wherein the application of said composition causes removal of said biofilm, wherein said biofilm comprises Porphyromonas gingiva/is.